Accessing the subarachnoid space via intrathecal needle placement can be done in nonhuman primates (NHPs) and other species to collect cerebral spinal fluid (CSF) or to deliver agents into the CSF.

The central nervous system (CNS) consists of the brain and spinal cord. Cerebrospinal fluid (CSF) is a clear, colorless liquid that surrounds and protects the CNS. It bathes the brain and spine in ...

We aimed to identify cerebrospinal fluid (CSF) biomarkers associated with neurodegeneration in individuals with and without CSF evidence of Alzheimer pathology. We investigated 287 Alzheimer’s Disease ...