This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...
During protein synthesis, the genetic information stored in DNA is first transcribed into mRNA. The mRNA then travels to the ribosome, where translation occurs. Here's how anticodons facilitate the ...
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Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends ...
AZoLifeSciences on MSN
Giant virus uses unique codon strategy to optimize host resource usage
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
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