Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

Spatial filter techniques, along with delivering real-time particle size measurement, offer several further attractions such as simple hardware requirements, ease of use and reasonable commercial cost ...

Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing. In less than a decade, ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...

Fluidized bed spray granulation is a versatile process that integrates the controlled spraying of a binder liquid onto fluidized particles, leading to the formation of agglomerates or granules with ...

Small molecules, tablets, capsules, soft gels, effervescence, gummies, and pills. These are all oral solid dosage (OSD) forms, a term that refers to a final drug product therapy that is ingested ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Granulation is the most crucial step in the manufacture of solid dosage forms. Granulation is the most crucial step in the manufacture of solid dosage forms because it provides the main physical ...

Iron ore granulation and sintering technology encompasses the processes that transform fine iron ore particles into coherent multicomponent agglomerates suitable for use in blast furnaces. Granulation ...

The last decade has seen an impressive growth in the research and mechanistic understanding of the agglomeration process, along with attempts to model the process. There have even been a few papers on ...