The fluorescence-imaging technology in cells allows study the cellular mechanisms of the organelles with multiple imaging approaches. Different fluorescent proteins work as protein tags in detecting ...

Biophysicists have developed control software that optimizes how fluorescence microscopes collect data on living samples. Their control loop, used to image mitochondrial and bacterial sites of ...

After it fills with cargo, the pit pinches off to form a clathrin-coated, membrane-bound vesicle inside the cell, which then proceeds to its proper destination. In cultured cells, hundreds of these ...

Conventional light microscopy has been instrumental for the study of cells and microorganisms; fluorescence microscopy has enabled visualization of even smaller cell features by selectively adding ...

Researchers commonly employ fluorescence microscopy to characterize molecular, cellular, and developmental processes in depth. Despite its benefits, scientists can face challenges when imaging their ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A device that can convert a smartphone or tablet into a fluorescence microscope for less than US $50 is presented in a proof-of-principle study in Scientific Reports. The authors suggest that the ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) have developed an innovative microscopy technique capable of improving the observation of living cells. The study, ...

Chip technology presents a whole different view on microscopy. Chips are compact and can integrate multiple functionalities. The scaling possibilities could allow chip-based microscopes to be produced ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...