Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...

An international team of scientists led from Sweden's Karolinska Institutet has for the first time mapped all the genes that are activated in the first few days of a fertilized human egg. The study, ...

Using human stem cells, scientists have created human embryo-like structures inside petri dishes. These lab-grown blobs develop multiple structures that mimic a human embryo after implantation into ...

When someone says the word embryo, what do you think of? Probably that picture you’ve seen a thousand times on a thousand different news articles: a translucent orb swelling with cytoplasm being ...

The majority of fertilized eggs die and are resorbed into the body. ZEISS Microscopy/Flickr, CC BY-SA As an evolutionary biologist whose career has focused on how embryos develop in a wide variety of ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...

Only about one out of three conceptions leads to birth. 1 Approximately a third of embryos fail to attach to the uterus, while another third is lost after the embryo implants. “Human reproduction is ...

Researchers have discovered a potential 'pause button' in the earliest stages of human development. Whether humans can control the timing of their development has long been debated. The new study ...