Quantifying the risk of cancer associated with pathogenic mutations in germline cancer susceptibility genes—that is, penetrance—enables the personalization of preventive management strategies.

Meta-analysis of diagnostic test accuracy studies is an increasingly pivotal approach in evidence-based medicine, enabling the synthesis of data from multiple investigations to assess the performance ...

Though it remains a common practice, requiring patients to have nothing by mouth (NPO) for several hours before percutaneous cardiovascular procedures doesn’t appear to have any advantages over ...

Meta-analysis is an objective examination of published data from many studies of the same research topic identified through a literature search. Through the use of rigorous statistical methods, it can ...

Does living in an unequal society make people unhappy? Not necessarily, reveals the largest study ever conducted on the ...

Objective To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise ...