Mitochondria are essential organelles that drive energy production, regulate apoptosis and orchestrate metabolic signalling within cells. Their dynamic nature underpins processes as diverse as ATP ...

Deferiprone（去铁酮，AbMole，M2617）作为一种铁螯合剂，在调控铁代谢和抑制铁死亡（Ferroptosis）方面展现出显著的研究价值。其作用机制主要通过调节铁稳态和抗氧化途径实现，Deferiprone（DFP，AbMole，M26 ...

The involvement of glial cells in Alzheimer's disease (AD) has been mostly viewed as a secondary adaptive response to ...

Area of Focus: mitochondrial quality control, cellular metabolism, immune responses and the mechanisms underlying neurodegenerative diseases. Fourteen years ago, Xin Qi joined the Department of ...

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...

Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

This study examined mitochondrial and nuclear-encoded mitochondrial DNA methylation in Indian patients with severe COVID-19 ...

Metabolic syndrome refers to having multiple conditions that increase the risk of health problems like diabetes, stroke and heart disease.Photograph: koto_feja/Getty Images Metabolic syndrome refers ...