In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...
RNA splicing involves the removal of non-coding introns and the joining of coding exons in precursor mRNA (pre-mRNA) to produce mature messenger RNA (mRNA). Splicing changes can lead to diseases, ...
Researchers analyzed gene expression and network connectivity across eight human tissues and found shared aging-related ...
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...
Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...
New research provides a mechanistic map of how genetic mutations disrupt RNA splicing in acute myeloid leukemia.
Our results demonstrate that differential connectivity analysis reveals significant transcriptional alterations that are not ...
Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the ...
Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...
An alternative splicing regulator previously implicated in calcium signaling in the heart ensures cell-type-specific mRNA processing of long neuronal mRNAs in the mouse brain.